Analog SFF, September 2010

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Fact 2008;128(9):38-48.
    23 Jain KK. The Handbook of Nanomedicine . Humana Press, Totowa, NJ. 2008.
    24 Naldini L. Medicine. "A comeback for gene therapy.” Science 2009;326(5954):805-6.
    25 Gene Therapy. In: Human Genome Project Information. A brief description of the current status of gene therapy. www.ornl.gov/hgmis/medicine/genetherapy.html
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Novelette: PUPA by David D. Levine
Extreme circumstances can require radical departures from even the most deeply rooted “traditons. . . ."
    A spasm of pain made Ksho drop her forelimb-brush.
    Xinecotic-ki Ksho always ached all over, from her mandibles to the tips of her third pair of limbs. Pain and hunger were the natural states of a Shacuthi juvenile—pain from constant rapid growth and hunger for the vast quantities of food she needed to sustain that growth—but this latest spasm was the bone-deep ache that meant her skin was getting to be too small. She had already molted seven times and knew this feeling well, but this next molt would be her last as a juvenile. After this molt she would pupate for three months, her ugly juvenile body replaced by a gleaming adult.
    She was thrilled. She was terrified.
    But for now, she had a job to do.
    Ksho bent down and scrabbled with clumsy, weak two-fingered hands for the brush on the rough cloth of the floor, wishing she had an adult's hands—gleaming three-fingered structures of chitin and bone, capable of powerful grasp and fine manipulation. Finally, using both of her first pair of hands, she managed to regain the brush and resumed her laborious progress to her parent Xinecotic's grooming chamber, waddling along on stumpy little hind limbs barely capable of supporting her growing weight.
    The delay probably saved her life.
    Ksho did not scrape at the door before entering the grooming chamber. The scraping-board was for adults; juveniles came and went as their duties required, with no more notice or need for permission than the air that cooled the corridor. She paused for a moment with one hand on the door latch, making sure she had a firm grip on the brush, and at that moment she heard voices from within.
    The unexpected sound made Ksho freeze, her skin tingling—an instinctive response honed over thousands of generations. Surely there could be no other adult in Xinecotic's grooming chamber at this hour? The hour of grooming was inviolate, a time of quiet contemplation. But life had been strange ever since they had traveled to this cold and desolate place, and it had only become stranger in the last few months. Ksho worked the lower door latch, slid the door open a crack, and poked one eye into the room.
    Xinecotic was not alone in her grooming chamber. Takacha, the head of the expedition, was there as well. Neither adult took any notice of Ksho's eye peeping around the door's edge. Ten or twelve of Ksho's sisters were also present, buffing and polishing their parent's gleaming limbs and torso. None of them seemed to be alarmed by Takacha's presence in Xinecotic's grooming chamber, but Ksho told herself she shouldn't expect her younger siblings to be as observant as she. She was the eldest, after all, nearly ready to pupate.
    "You should have realized,” Takacha was saying, “that you wouldn't be able to maintain this deception forever.” As she spoke, a flavor of apprehension drifted through the slightly open door to Ksho's fingers. Both adults were nervous, verging on terrified. Why?
    "Don't do this, Takacha.” Xinecotic was holding perfectly still, most unlike the usual rolling and preening of an adult being groomed. “You can stop this madness now, before any permanent harm is done. I'm authorized to offer clemency if you halt the operation immediately and surrender."
    Takacha chuttered, antennae lifting, as though Xinecotic had just said something funny. “Clemency.” She raised one hand, and Ksho's already sour stomachs soured still further, with fear, as she realized Takacha held a weapon

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