people’s lives. Much of the time, when it happens, we label it mental illness, even though it’s not only or even at all occurring inside people’s psyches. Addiction to alcohol or another mood-altering drug is a common positive-feedback process. Imagine a person who enjoys alcohol, perhaps a bit too much. He has a quick three or four drinks. His blood alcohol level spikes sharply. This can be extremely exhilarating, particularly for someone who has a genetic predisposition to alcoholism. 23 But it only occurs while blood alcohol levels are actively rising, and that only continues if the drinker keeps drinking. When he stops, not only does his blood alcohol level plateau and then start to sink, but his body begins to produce a variety of toxins, as it metabolizes the ethanol already consumed. He also starts to experience alcohol withdrawal, as the anxiety systems that were suppressed during intoxication start to hyper-respond. A hangover is alcohol withdrawal (which quite frequently kills withdrawing alcoholics), and it starts all too soon after drinking ceases. To continue the warm glow, and stave off the unpleasant aftermath, the drinker may just continue to drink, until all the liquor in his house is consumed, the bars are closed and his money is spent.
The next day, the drinker wakes up, badly hungover. So far, this is just unfortunate. The real trouble starts when he discovers that his hangover can be “cured” with a few more drinks the morning after. Such a cure is, of course, temporary. It merely pushes the withdrawal symptoms a bit further into the future. But that might be what is required, in the short term, if the misery is sufficiently acute. So now he has learned to drink to cure his hangover. When the medication causes the disease, a positive feedback loop has been established. Alcoholism can quickly emerge under such conditions.
Something similar often happens to people who develop an anxiety disorder, such as agoraphobia. People with agoraphobia can become so overwhelmed with fear that they will no longer leave their homes. Agoraphobia is the consequence of a positive feedback loop. The first event that precipitates the disorder is often a panic attack. The sufferer is typically a middle-aged woman who has been too dependent on other people. Perhaps she went immediately from over-reliance on her father to a relationship with an older and comparatively dominant boyfriend or husband, with little or no break for independent existence.
In the weeks leading up to the emergence of her agoraphobia, such a woman typically experiences something unexpected and anomalous. It might be something physiological, such as heart palpitations, which are common in any case, and whose likelihood is increased during menopause, when the hormonal processes regulating a women’s psychological experience fluctuate unpredictably. Any perceptible alteration in heart-rate can trigger thoughts both of heart attack and an all-too-public and embarrassing display of post-heart attack distress and suffering (death and social humiliation constituting the two most basic fears). The unexpected occurrence might instead be conflict in the sufferer’s marriage, or the illness or death of a spouse. It might be a close friend’s divorce or hospitalization. Some real event typically precipitates the initial increase in fear of mortality and social judgment. 24
After the shock, perhaps, the pre-agoraphobic woman leaves her house, and makes her way to the shopping mall. It’s busy and difficultto park. This makes her even more stressed. The thoughts of vulnerability occupying her mind since her recent unpleasant experience rise close to the surface. They trigger anxiety. Her heart rate rises. She begins to breathe shallowly and quickly. She feels her heart racing and begins to wonder if she is suffering a heart attack. This thought triggers more anxiety. She breathes even more shallowly, increasing the levels of carbon dioxide in her blood.
Gina Whitney, Leddy Harper